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5 Best Medicines of 2026

Last Updated - 2026/01/31

1
Best Choice

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Buckley's

Buckley's Cough Syrup, Complete Extra Strength Mucus Relief, Cough & Cold & Flu Medicine, Headache and Sinus Relief, 250 mL (Packaging May Vary)

Buckley's

CA$15.17

CA$16.39
(7% Off)

More Details
Main highlights
- This package includes one 250 mL bottle of Buckley's Complete Plus Extra Strength Mucus Relief Syrup
- Manage your cold symptoms with Buckley's Complete Plus Extra Strength Mucus Relief Syrup, providing fast-acting relief of minor aches and pains, fever and chills, sore throat pain, wet cough, nasal and sinus congestion, and chest congestion
- Formulated for adults and children 12 years and older, take 2 teaspoons (10 mL) every 4-6 hours (do not take more than 40 mL in 24 hours). Do not take more than directed. If preferred, mix with equal parts honey
- For medicinal ingredients, each teaspoon (5 mL) of Buckley's Complete contains 325 mg acetaminophen for reducing fever and relieving aches and pain, 200 mg of the guaifenesin expectorant to loosen mucus and phlegm buildup, and 20 mg of menthol to suppress your cough and relieve nasal congestion
CA$15.17
CA$16.39 (7% Off)
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

NEOCITRAN

NEOCITRAN® ES Cold & Sinus Night Lemon

NEOCITRAN

CA$13.57

More Details
Main highlights
- Try the daytime formula from NeoCitran for non-drowsy relief during the day
- Suitable for adults and children ages 12 and older
- NeoCitran's most popular formula provides effective relief from sore throat pain, headache, sinus and nasal congestion, runny nose, and sneezing so you can rest
- Extra-strength nighttime cold and sinus medicine
- Dissolve the contents of a single-dose pouch in boiling water to create a soothing, lemon-flavored bedtime beverage
CA$13.57
3

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct

Tylenol

CA$12.77

More Details
Main highlights
- Tylenol Extra Strength Cold Daytime + Nightime Cool Burst eZ Tabs, 24 + 16 pack, relieves symptoms when colds strike so you can get back to your normal, whatever that is
- Get effective relief of nasal congestion, dry cough, fever, aches and pain, runny nose and sneezing
- Each package contains 40 tablets: 24 Daytime and 16 Nighttime tablets; eZ Tabs format is easy to swallow and provides fast and effective relief
- Each Nighttime tablet also contains 2 mg of Chlorpheniramine Maleate as an antihistamine for runny nose and sneezing. Nighttime relief so you can rest.
- Each Daytime and Nighttime tablet contains 500 mg of Acetaminophen to help relieve pain and reduce fever, 10 mg of Dextromethorphan Hydrobromide for cough suppression, and 5 mg of Phenylephrine Hydrochloride for nasal decongestion
CA$12.77
4

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct

Tylenol

CA$12.13

CA$12.77
(5% Off)

More Details
Main highlights
- Tylenol Extra Strength Cold Daytime + Nightime Cool Burst eZ Tabs, 24 + 16 pack, relieves symptoms when colds strike so you can get back to your normal, whatever that is
- Get effective relief of nasal congestion, dry cough, fever, aches and pain, runny nose and sneezing
- Each package contains 40 tablets: 24 Daytime and 16 Nighttime tablets; eZ Tabs format is easy to swallow and provides fast and effective relief
- Each Nighttime tablet also contains 2 mg of Chlorpheniramine Maleate as an antihistamine for runny nose and sneezing. Nighttime relief so you can rest.
- Each Daytime and Nighttime tablet contains 500 mg of Acetaminophen to help relieve pain and reduce fever, 10 mg of Dextromethorphan Hydrobromide for cough suppression, and 5 mg of Phenylephrine Hydrochloride for nasal decongestion
CA$12.13
CA$12.77 (5% Off)
5
Best Value
12% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

BENYLIN
12% Off

BENYLIN Extra Strength Cold and Sinus Caplets, Relieves Cold and Sinus symptoms, Daytime and Nighttime, Convenience Pack, 20ct

BENYLIN

CA$7.44

CA$8.47
(12% Off)

More Details
Main highlights
- Night tablets also contain 2 mg of antihistamine Chlorpheniramine Maleate to relieve runny nose and sneezing
- Get fast, effective relief of sinus pain, nasal congestion, headache and fever
- Each package contains 20 tablets with 10 Day tablets and 10 Night tablets
- Both Day and Night tablets contain 5 mg of decongestant Phenylephrine Hydrochloride to relieve nasal congestion and 500 mg of analgesic Acetaminophen to relieve sinus pain, headache and fever
- Benylin Extra Strength Cold and Sinus Day/Night Tablets, 20 Count, are a portable and convenient solution to relief your cold and sinus symptoms during the day and night
CA$7.44
CA$8.47 (12% Off)

5 Best Medicines of 2026

Buckley's Cough Syrup, Complete Extra Strength Mucus Relief, Cough & Cold & Flu Medicine, Headache and Sinus Relief, 250 mL (Packaging May Vary)

NEOCITRAN® ES Cold & Sinus Night Lemon

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct

BENYLIN Extra Strength Cold and Sinus Caplets, Relieves Cold and Sinus symptoms, Daytime and Nighttime, Convenience Pack, 20ct

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NEOCITRAN® ES Cold & Sinus Night Lemon

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